Antigen Test for COVID-19: How Is It Different from Coronavirus Testing

rapid antigen test for covid19

 

What is Rapid Antigen Test for COVID-19?

 

The Rapid Antigen Detection Test (RADT) for COVID-19 is a rapid point-of-care nasopharyngel swab test that directly detects the presence or absence of coronavirus antigen in the patient’s body, generating diagnosis results within 30 minutes. These tests are designed to detect a specific protein in the virus that elicits the body’s immune response.

 

RT-PCR, though highly accurate, requires complex bio safety compliant set ups and takes longer to give a result. We are thus seeing longer turnaround times as the number of cases rise. The antigen testing solves this problem to an extent as apart from being fast, it is highly specific and thus positive results are highly accurate.

 

How does an antigen test work?

 

An antigen is a molecule capable of stimulating an immune response. They may be proteins, polysaccharides, lipids or nucleic acids. Each antigen has distinct surface features that are recognized by the immune system.

SARS-CoV-2, the virus that causes COVID-19, has several known antigens, including its nucleocapsid phosphoprotein and spike glycoprotein, which are the visible protrusions on its surface.

An antigen test reveals if a person is currently infected with a pathogen such as the SARS-CoV-2 virus. Once the infection has gone, the antigen disappears. Unlike nucleic acid based tests such as PCR, which detect the presence of genetic material, antigen tests detect proteins or glycans, such as the spike proteins found on the surface of the SARS-CoV-2. They usually provide test results rapidly, are relatively cheap, and can be more amenable to point-of-care use, which could make them more suitable for testing in the community and in remote regions.

 

Where will the Rapid Detection Test be used?

 

According to the ICMR, the antigen test may be performed under strict medical supervision in the following settings:

  • In the containment zones to check the symptomatic influenza-like illnesses (ILI).
  • In the containment zones to test asymptomatic high risk contacts of the confirmed cases with other chronic systemic illnesses within 5 to 10 days of contact.
  • In healthcare settings, the antigen test may be used for people showing ILI symptoms, asymptomatic cancer patients, immunosuppressed individuals, elderly patients with other ailments and those undergoing dental procedures, non-surgical procedures like dialysis or surgeries which generate aerosol.

 

Can an Antigen Test diagnose the COVID-19?

 

The rapid detection test kit has been able to achieve 99.3% to 100% accuracy in detecting the true negativity. However, the specificity to discover the true positive is between 50.6% to 80%. Thus, testing must be done by maintaining the kit temperature between 2° and 30°C, and the kit will be used in containment zones or hotspots and hospital settings only.

 

antigen testing and coronavirus testing


How is the rapid antigen test different from Coronavirus Testing?

 

The significant difference between a Coronavirus Test and an Antigen Test is technology and time. For the diagnosis of COVID-19, RT-PCR test takes a minimum of 2-5 hours, including sample collection. On the other hand, a rapid antigen detection test (RADT) takes a maximum duration of 30 minutes for interpreting a positive or negative test.

 

What are the limitations of an antigen test’s results?

 

While the antigen test can be done in less time, it has certain limitations:

  • The negative results from an antigen test may need to be confirmed with a molecular PCR test.
  • Sample collection in the hospital setting is necessary. It cannot be used as a generalized test as claimed by many manufacturers.

 

Many laboratories and manufacturers, across the globe, are trying to develop testing kits, and scientists and researchers are working to develop the vaccination. However, people are advised to stay away from false claims and must follow the official channels and mediums to receive information.

Book Test

Plasma Therapy for Covid-19 Treatment: Procedure, Risk in Coronavirus

Plasma Therapy for Covid-19 In India

 

What is Plasma Therapy?

 

Plasma therapy is used for treating several infectious diseases. Convalescent-plasma therapy is a type of therapy in which blood plasma from recovered patients is administered to people who are currently suffering from the same disease. Convalescent-plasma therapy is being used in several clinical trials across the world for the treatment of COVID-19. In the list of countries using plasma therapy for treating coronavirus patients, names like India, UK, USA, etc feature.
Read More

Book Test

Hydroxychloroquine For Coronavirus: Uses, Precautions, Side Effects

 

Hydroxychloroquine For Coronavirus Covid-19

UNDER STUDY FOR COVID-19

 

Hydroxychloroquine (HCQS), along with its byproduct drug Chloroquine, is still under study, and it is tagged for the possible treatments for COVID-19. This drug is only used out of circumstances, and it is still not approved by the FDA. Do not use these medications to treat COVID-19 unless your doctor specifically recommends you to do so. If you carefully follow through the descriptions, you will discover that this drug also has a brand name: Plaquenil. Hydroxychloroquine, which is used for possible treatments for COVID-19, comes in the form of oral tablets. It is suggested that you do not use these medications to treat COVID-19 unless your doctor specifically recommends that you do so.

Read More

Book Test

Aarogya Setu App: Everything About India’s COVID-19 Tracker

Aarogya Setu App - Covid 19 Cases Near Me Tracker India


What is Aarogya Setu App?

 

India has been at the forefront of efficient management of COVID-19 pandemic with timely lockdown since the last week of March 2020. The Ministry of Electronics and IT of the Government of India released India’s COVID-19 tracker tool called the Aarogya Setu app online. The Arogya Setu is an application that tracks COVID-19 cases around an individual to keep him/ her informed if they have come across or are in close contact with someone who has tested positive while Covid -19 testing.

The Aarogya Setu application that tracks COVID-19 cases around you uses Bluetooth technology and location of your phone, so you need to keep both these switched on at all times. The Arogya Setu app online will alert you if you unknowingly come in close contact or proximity with someone who has tested positive, even before you develop any symptoms.

Read More

Book Test

5 Ways To Boost or Increase Immunity For COVID-19 Coronavirus

immunity boosting foods for covid19 coronavirus

With the spread of the COVID-19, the whole world is fighting it together. Although there is no vaccination available so far, the best way to fight this pandemic is to stay away from it by taking precautions, building immunity, and abiding by the government regulations. In this difficult time, SRL Diagnostics is also committed to providing its services for the country, and has been approved by ICMR, Govt. of India for sample collection, diagnosis and COVID-19 testing.

How to Protect yourself from Coronavirus

 

People can adopt several measures as coronavirus precautions. Given below are some of the coronavirus tips that everyone can easily follow:

Read More

Book Test

Coronavirus Tips – 7 Preventive Measures To Stay Safe Indoors

 

coronavirus tips stay safe home

 

We are amid challenging times. Therefore, SRL has come up with some common safety tips that can safeguard you from the pandemic coronavirus disease (COVID-19). People across the globe are panicking due to the alarming conditions of the coronavirus spread. In this troublesome time, you can still take steps to save yourself from this pandemic.

However, there is no availability of an antidote, vaccine, or other treatments to combat Coronavirus at this time. For your safety, the basic protective measures against COVID-19 can work amazingly. What is the guarantee of staying healthy at home? How can you keep the Coronavirus away staying inside the house?

To stay safe indoors, you need to understand the most important and basic preventive tips of Coronavirus. Careless behaviour towards health can be vicious.Read More

Book Test

5 Best Home Workout Exercises During Coronavirus Lockdown

5 Best Home Workout Exercises During Coronavirus Lockdown

Home Workout Exercises During Coronavirus Lockdown

 

Until a few months back, before the novel coronavirus was in our country, many people had excuses for skipping gym routines after getting exhausted at work. But, now that we all are under strict lockdown at our homes and aren’t finding much to do, full body workout at home has become a central part of our daily routine for many of us. Whether it is to increase workout our immunity and fitness, or to maintain a slim physique during this lockdown or even just to pass the time doing something constructive, we have understood the importance of exercise in our life.

So while you follow the protocol of the lockdown, maintain proper hygiene and social distancing and stay indoors. You can also follow these home workout exercises for Lockdown to keep fit and practice them even when the COVID-19 outbreak is over.

These five routines are the best home exercises during Coronavirus lockdown  to keep your body in good health and shape:

Read More

Book Test

Coronavirus – Symptoms, Types, Transmission & Treatment

coronavirus precaution tips

About Coronavirus:

 

Infectious bronchitis virus (IBV) was the first coronavirus to be isolated from domestic fowls in the late 1930s. These viruses infect the upper respiratory system of the mammals including humans. Various coronavirus types lead to various health issues. Most of the coronaviruses are not harmful. It is advisable to consult expert doctors for coronavirus diagnosis. Depending upon the type of virus and the damage caused, the doctors implement coronavirus treatment in a patient-specific manner.

 

Symptoms, Types and Diagnosis:

 

These viruses majorly cause cold to different intensities among humans. The other coronavirus symptoms include:

Read More

Book Test

Breaking the Myths Surrounding Coronavirus

Coronavirus Symptoms

 

Coronavirus: Signs, Symptoms, Myths & Prevention Tips

 

With an increase in number of confirmed coronavirus  (COVID-19) cases making news every hour, the panic & anxiety around it also continues to make round. While it is important to be informed, the higher value should be placed on being correctly informed.

Here’s a list of Coronavirus Myths around the epidemic that you need to burst immediately.
 Read More

Book Test